Article
Novel mutations in transthyretin gene associated with hepatocellular carcinoma.
Molecular carcinogenesis - 1 Jan 2018
P Katare Deepshikha, Malik Shabnam, J Mani Ruchi, Ranjpour Maryam, Jain Swatantra K
Abstract excerpt
Hepatocellular carcinoma (HCC) is one of the major health problems with increasing incidence worldwide. We report the elevation in transthyretin (TTR) expression following HCC induction using diethylnitrosamine (DEN) and 2-aminoacetylfluorine (2-AAF) in male Wistar rats. The increase in its expression took place at very early stage and remained elevated throughout HCC progression. The analysis of TTR gene in HCC...
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