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Article

A systematic approach to the assessment of known TNF-alpha polymorphisms in Graves' disease.

Genes and immunity - 1 Jun 2004

Simmonds M J, Heward J M, Howson J M M, Foxall H, Nithiyananthan R, Franklyn J A, Gough S C L

Abstract excerpt

Single-nucleotide polymorphisms (SNPs) within the tumour necrosis factor alpha (TNF-alpha) gene on chromosome 6p21.3 have been associated with many autoimmune diseases; however, results have been conflicting and accurate allele frequencies have never been established in a UK Caucasian population. The aim of this study was to assess the frequency of 22 known TNF-alpha SNPs in a UK Caucasian control population and...

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Source

Identifiers

PMID: 15057268
DOI: 10.1038/sj.gene.6364066

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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