Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of tumor necrosis factor and human leukocyte antigen DRB1 alleles with Graves' ophthalmopathy.

Human immunology - 1 Jun 2004

Bednarczuk Tomasz, Hiromatsu Yuji, Seki Naoko, Płoski Rafał, Fukutani Tomoka, Kuryłowicz Alina, Jazdzewski Krystian, Chojnowski Krzysztof, Itoh Kyogo, Nauman Janusz

Abstract excerpt

Tumor necrosis factor (TNF)-alpha plays a central role in the development of ophthalmopathy in patients with Graves' disease (GD). The aim of this study was to investigate the association of TNF promoter polymorphisms at positions -1031 (T-1031C), -863 (C-863A), -857 (C-857T), -308 (G-308A), and -238 (G-238A) with Graves' ophthalmopathy (GO). We studied the distribution of TNF and human leukocyte antigen (HLA)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Graves Disease
Share to HLA-DR Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-DRB1 Chains

Share to Linkage Disequilibrium

Share to Poland

Share to Promoter Regions, Genetic

Share to Tumor Necrosis Factor-alpha

Share to White People

Source

Identifiers

PMID: 15219383
DOI: 10.1016/j.humimm.2004.02.033

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of tumor necrosis factor and human leukocyte antigen DRB1 alleles with Graves' ophthalmopathy.PMID 15219383Read ↗

Tumor necrosis factor alpha (TNF-alpha) polymorphisms in Chinese patients with Graves' disease.Semantic proximity Read ↗

Association of TNF-α promoter polymorphism and Graves' disease: an updated systematic review and meta-analysis.Semantic proximity Read ↗

HLA-DRB1*03 is a susceptibility gene in patients with Graves' disease with and without ophthalmopathy.Semantic proximity Read ↗

Association of TNF-alpha, TNF-beta, IFN-gamma and IL-1Ra gene polymorphisms with Graves' disease in the Thai population.Semantic proximity Read ↗

TNF gene polymorphisms in Graves' disease: TNF-308 A/G meta-analysis.Semantic proximity Read ↗

Association of tumour necrosis factor alpha (TNF-alpha) polymorphisms with Graves' disease: A meta-analysis.Semantic proximity Read ↗

Susceptibility genes in Graves' ophthalmopathy: searching for a needle in a haystack?Semantic proximity Read ↗

Association of NFKB1 -94ins/del ATTG promoter polymorphism with susceptibility to and phenotype of Graves' disease.Semantic proximity Read ↗

Significance of HLA in the development of Graves' orbitopathy.Semantic proximity Read ↗

Genetic susceptibility to Graves' ophthalmopathy: the role of polymorphisms in proinflammatory cytokine genes.Semantic proximity Read ↗

Graves' disease and gene polymorphism of TNF-α, IL-2, IL-6, IL-12, and IFN-γ.Semantic proximity Read ↗

A systematic approach to the assessment of known TNF-alpha polymorphisms in Graves' disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.