Article
SNPs in the TNF-α gene promoter associated with Behcet's disease in Moroccan patients.
Rheumatology (Oxford, England) - 1 Sept 2012
Radouane Asmaa, Oudghiri Mounia, Chakib Abdelfettah, Bennani Siham, Touitou Isabelle, Barat-Houari Mouna
Abstract excerpt
OBJECTIVE: Behçet's disease (BD) is a multisystemic inflammatory disease, mainly characterized by recurrent oral and genital ulcers (GUs), skin lesions and uveitis. Several genetic factors such as the TNF-α gene have been evaluated as contributors to the pathogenesis of BD. We aimed to evaluate the association between six TNF-α SNPs and susceptibility to BD, or the major clinical manifestations, in Moroccan...
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