Article
Association of TNF-α polymorphisms with adult dermatomyositis and systemic lupus erythematosus in Bulgarian patients.
International journal of dermatology - 1 Dec 2012
Dourmishev Lyubomir, Kamenarska Zornitsa, Hristova Maria, Dodova Rumyana, Kaneva Radka, Mitev Vanio
Abstract excerpt
BACKGROUND: Single-nucleotide polymorphisms (SNPs) of tumor necrosis factor-alpha (TNF-α) have been implicated in various autoimmune diseases; however, the results are quite controversial, and there is still no widely accepted opinion about their role in the pathology of the autoimmune diseases. This is a pilot study to investigate the association of six SNPs of the TNF-α gene with the risk of adult...
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