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Article

A male-specific role for <i>SOX9</i> in vertebrate sex determination

1 Sept 1996

Abstract excerpt

Mutation analyses of patients with campomelic dysplasia, a bone dysmorphology and XY sex reversal syndrome, indicate that the SRY-related gene SOX9 is involved in both skeletal development and sex determination. To clarify the role SOX9 plays in vertebrate sex determination, we have investigated its expression during gonad development in mouse and chicken embryos. In the mouse, high levels of Sox9 mRNA were found...

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Identifiers

PMID: 8787755
DOI: 10.1242/dev.122.9.2813

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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A male-specific role for <i>SOX9</i> in vertebrate sex determinationPMID 8787755Read ↗

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The Sry-related gene Sox9 is expressed during chondrogenesis in mouse embryos.Semantic proximity Read ↗

Heterozygous deletion of Sox9 in mouse mimics the gonadal sex reversal phenotype associated with campomelic dysplasia in humans.Semantic proximity Read ↗

Testicular Differentiation Occurs in Absence of R-spondin1 and Sox9 in Mouse Sex ReversalsSemantic proximity Read ↗

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Up‐regulation of SOX9 in human <i>sex‐determining region on the Y chromosome (SRY)</i>‐negative XX malesSemantic proximity Read ↗

SEX IN THE 90s:<i>SRY</i>and the Switch to the Male PathwaySemantic proximity Read ↗

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