Article
Correlation of immunohistochemical staining and mutations of p53 in human hepatocellular carcinoma.
Oncology reports - 1 Jan 2000
Hsia C C, Nakashima Y, Thorgeirsson S S, Harris C C, Minemura M, Momosaki S, Wang N J, Tabor E
Abstract excerpt
Mutations of the p53 tumor suppressor gene are common in hepatocellular carcinomas (HCCs). Detection of mutations by sequencing provides more information than immunohistochemical staining, but the equipment needed and the time required make it less practical for use in large-scale studies or in studies in developing countries. The degree of correlation between results obtained with these two methods has been...
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