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Article

Interpretation of P53 Immunohistochemistry in Endometrial Carcinomas: Toward Increased Reproducibility.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Jan 2019

Köbel Martin, Ronnett Brigitte M, Singh Naveena, Soslow Robert A, Gilks C Blake, McCluggage W Glenn

Abstract excerpt

P53 immunohistochemistry has evolved into an accurate surrogate reflecting the underlying TP53 mutation status of a tumor, and has utility in the diagnostic workup of endometrial carcinomas. Recent work predominantly carried out in tubo-ovarian high-grade serous carcinoma has revealed 4 main patterns of p53 staining (normal/wild-type, complete absence, overexpression, and cytoplasmic); the latter 3 patterns are...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29517499
DOI: 10.1097/PGP.0000000000000488
PMCID: PMC6127005

Genes

TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interpretation of P53 Immunohistochemistry in Endometrial Carcinomas: Toward Increased Reproducibility.PMID 29517499Read ↗

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