Article
Correlation between malignancy grade and p53 gene in relation to thymidine phosphorylase activity in colorectal cancer patients.
Oncology reports - 1 Jan 2000
Aoki Tatsuya, Katsumata Kenji, Tsuchida Akihiko, Tomioka Hidenori, Koyanagi Yasuhisa
Abstract excerpt
We studied 89 colorectal cancer patients conducting immunohistological staining of thymidine phosphorylase (TP) and investigated correlation between the enzyme activity levels, clinicopathologic factors and patient prognosis. Based on TP expression level, we also assessed p53, an anti-oncogene related to hematogenesis and nucleic acid metabolism. TP staining results were classified into: i) strongly stained group...
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