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Article

Paraoxonase polymorphisms PON1 192 and 55 and longevity in Italian centenarians and Irish nonagenarians. A pooled analysis.

Experimental gerontology - 1 Apr 2004

Rea Irene M, McKeown Pascal P, McMaster Dorothy, Young Ian S, Patterson Chris, Savage Maurice J, Belton Christine, Marchegiani Francesca, Olivieri Fabiola, Bonafe Massimiliano, Franceschi Claudio

Abstract excerpt

BACKGROUND: PON1, an arylesterase, associated with high density lipoprotein (HDL), protects low density lipoprotein (LDL) against oxidative modification. Common polymorphisms PON1 55 (L/M) and 192 (Q/R) in the PON1 gene associate with atherosclerosis and heart disease. Because long-lived people s...

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Source

Identifiers

PMID: 15050299
DOI: 10.1016/j.exger.2003.11.019

Genes

PON1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15050299-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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