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Article

High-density lipoprotein cholesterol and paraoxonase 1 (PON1) genetics and serum PON1 activity in prepubertal children in Spain.

Clinical chemistry and laboratory medicine - 1 Jan 2008

Garcés Carmen, López-Simón Laura, Rubio Rafael, Benavente Mercedes, Cano Beatriz, Ortega Henar, de Oya Manuel

Abstract excerpt

BACKGROUND: Oxidative stress plays an important role in atherosclerosis. Paraoxonase 1 (PON1) is a high-density lipoprotein (HDL)-associated enzyme that inhibits low-density lipoprotein (LDL) oxidation and may play a protective role against coronary heart disease. The aim of this study was to analyze the relationship between HDL-cholesterol (HDL-C) and PON1 in a Spanish prepubertal population with high plasma...

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Identifiers

PMID: 18601602
DOI: 10.1515/CCLM.2008.163

Genes

PON1

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