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Article

Paraoxonase activity and genotype predispose to successful aging.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Jun 2006

Marchegiani Francesca, Marra Maurizio, Spazzafumo Liana, James Richard W, Boemi Massimo, Olivieri Fabiola, Cardelli Maurizio, Cavallone Luca, Bonfigli Anna Rita, Franceschi Claudio

Abstract excerpt

The paraoxonase 1 codon 192 R allele has been previously reported to have a role in successful aging. The relationship between PON1 genotypes, enzymatic activity, and mass concentration was evaluated in a group of 229 participants from 22 to 104 years of age, focusing our attention on nonagenaria...

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Source

Identifiers

PMID: 16799134
DOI: 10.1093/gerona/61.6.541

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16799134-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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