Analysis of HLA-DQA1 and -DQB1 genes in Mexican Americans with insulin-dependent diabetes mellitus.

doi:10.1111/j.1399-0039.1993.tb02240.x

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Article

Analysis of HLA-DQA1 and -DQB1 genes in Mexican Americans with insulin-dependent diabetes mellitus.

Tissue antigens - 1 Aug 1993

Sanjeevi C B, Zeidler A, Shaw S, Rotter J, Nepom G T, Costin G, Raffel L, Eastman S, Kockum I, Wassmuth R

Abstract excerpt

Mexican American patients (n = 35) with insulin-dependent diabetes mellitus (IDDM) and control subjects (n = 39) were HLA-DQA and DQB typed by the polymerase chain reaction technique combined with allele-specific oligonucleotide probes. Either DQB1*0302 or DQB1*0201 was present among 91% (32/35)...

Topics

Adult
Alleles
Blotting, Southern
Child
Diabetes Mellitus, Type 1
Disease Susceptibility
Gene Frequency
Genes, MHC Class II
Genetic Predisposition to Disease
HLA-DQ Antigens
HLA-DQ alpha-Chains
HLA-DQ beta-Chains
Haplotypes
Humans
Mexican Americans

Source

Open in PubMed

Identifiers

PMID: 7903490
DOI: 10.1111/j.1399-0039.1993.tb02240.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7903490-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Oligonucleotide Probes

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length