Article
[Endophenotype--a new concept for biological characterization of psychiatric disorders].
Der Nervenarzt - 1 Mar 2004
Zobel A, Maier W
Abstract excerpt
In the field of psychiatric genetics, the concept of endophenotypes is presently receiving high popularity. Current difficulties in the search for susceptibility genes of complex diseases have been attributed to the etiological heterogeneity of the clinical, psychopathologically defined phenotype of the disease. Neurobiological correlates of the disease which are genetically influenced and stable over time are...
Topics
- Alcoholism
- Alzheimer Disease
- Bipolar Disorder
- Depressive Disorder, Major
- Genetic Determinism
- Genetic Markers
- Genetic Predisposition to Disease
- Humans
- Neurobiology
- Pedigree
- Phenotype
- Schizophrenia