Article
[Endophenotypes: the molecular biology point of view].
L'Encephale - 1 Dec 2012
Belzeaux R, Ibrahim E C, Cermolacce M, Fakra E, Azorin J M
Abstract excerpt
Endophenotypes are proposed for a better understanding of the molecular substrate underlying psychiatric disorders vulnerability. In this review, we discuss key points of the definition of endophenotypes from the molecular biology point of view. First, we examine the concept of heritability of endophenotype, which does not directly explain the molecular mechanisms responsible for the studied disorder Indeed, we...
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