Article
[Schizophrenia and/or bipolar disorder: neurobiological endophenotypes].
L'Encephale - 1 Dec 2012
Adida M, Azorin J-M, Fakra E, Belzeaux R, Kaladjian A, Pomietto P, Corréard N
Abstract excerpt
BACKGROUND: The term endophenotype was used by Gottesman (1991) to describe a trait that may be intermediate on the chain of causality from genes to diseases. Some family relatives of affected patients also carry the endophenotype, although not the disease phenotype. The increased penetrance of the endophenotype, and its closer relationship to the gene than that of the phenotype proper, are expected to help...
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