Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Endophenotype 2.0: updated definitions and criteria for endophenotypes of psychiatric disorders, incorporating new technologies and findings.

Translational psychiatry - 24 Dec 2024

Liu Chunyu, Gershon Elliot S

Abstract excerpt

Recent genetic studies have linked numerous loci to psychiatric disorders. However, the biological pathways that connect these genetic associations to psychiatric disorders' specific pathophysiological processes are largely unclear. Endophenotypes, first defined over five decades ago, are heritable traits, independent of disease state that are associated with a disease, encompassing a broad range of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endophenotypes
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mental Disorders

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 39719446
DOI: 10.1038/s41398-024-03195-1
PMCID: PMC11668880

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Endophenotype 2.0: updated definitions and criteria for endophenotypes of psychiatric disorders, incorporating new technologies and findings.PMID 39719446Read ↗

The endophenotype concept in psychiatry: etymology and strategic intentions.Semantic proximity Read ↗

The concept of endophenotypes in psychiatric diseases meeting the expectations?Semantic proximity Read ↗

Arguments for the sake of endophenotypes: examining common misconceptions about the use of endophenotypes in psychiatric genetics.Semantic proximity Read ↗

[Endophenotypes: the molecular biology point of view].Semantic proximity Read ↗

Endophenotypes in the genetic analyses of mental disorders.Semantic proximity Read ↗

Mapping Risk from Genes to Behavior: The Enduring and Evolving Influence of Irving Gottesman's Endophenotype Concept.Semantic proximity Read ↗

[Endophenotype--a new concept for biological characterization of psychiatric disorders].Semantic proximity Read ↗

Endophenotypes for psychiatric disorders: ready for primetime?Semantic proximity Read ↗

Endophenotype and Psychiatry: an Interesting Combination.Semantic proximity Read ↗

Genomic substrates of neurophysiological endophenotypes: where we've been and where we're going.Semantic proximity Read ↗

Endophenotypes as quantitative risk factors for psychiatric disease: rationale and study design.Semantic proximity Read ↗

Knowns and unknowns for psychophysiological endophenotypes: integration and response to commentaries.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.