Article
The concept of endophenotypes in psychiatric diseases meeting the expectations?
Pharmacopsychiatry - 1 Sept 2008
Puls I, Gallinat J
Abstract excerpt
Although the prominent role of genetics in psychiatric diseases has been established in various family, twin and adoption studies over the last decades, the identification of concrete contributing genes has been demanding. The reasons for this are manifold, including inconsistencies in psychiatric classification systems, complexity and heterogeneity of psychiatric disorders, epistatic effects and intervening...
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