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Article

Molecular basis of antigen recognition by insulin specific T cell receptor.

Immunology letters - 15 Feb 2004

Sugiyama Shigeru, Kohyama Masako, Oda Masayuki, Azuma Takachika, Wither Joan E, Hozumi Nobumichi

Abstract excerpt

The TCR alpha/beta chains recognize antigen peptides bound to the groove of the MHC class II molecule. The crystal structure analyses of the TCR/peptide/MHC class II complexes have revealed that the Valpha chains play a significant role in antigen recognition. However, molecular details which amino acid residues of the Valpha chain are able to contribute to fine antigen specificity are not clearly understood....

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Source

Identifiers

PMID: 15019281
DOI: 10.1016/j.imlet.2003.11.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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