Article
Striking antigen recognition diversity in the Atlantic salmon T-cell receptor alpha/delta locus.
Developmental and comparative immunology - 1 Jan 2008
Yazawa Ryosuke, Cooper Glenn A, Hunt Peter, Beetz-Sargent Marianne, Robb Adrienne, Conrad Melanie, McKinnel Linda, So Stacy, Jantzen Stuart, Phillips Ruth B, Davidson William S, Koop Ben F
Abstract excerpt
The complete TCR alpha/delta locus of Atlantic salmon (Salmo salar) has been characterized and annotated. In the 900 kb TCR alpha/delta locus, 292 Valpha/delta segments and 123 Jalpha/delta segments were identified. Of these, 128 Valpha/delta, 113 Jalpha, and a Jdelta segment appeared to be functional as they lacked frame shifts or stop codons. This represents the largest repertoire of Valpha/delta and Jalpha...
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