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Article

Preextinction viral RNA can interfere with infectivity.

Journal of virology - 1 Apr 2004

González-López Claudia, Arias Armando, Pariente Nonia, Gómez-Mariano Gema, Domingo Esteban

Abstract excerpt

When the error rate during the copying of genetic material exceeds a threshold value, the genetic information cannot be maintained. This concept is the basis of a new antiviral strategy termed lethal mutagenesis or virus entry into error catastrophe. Critical for its success is preventing survival of residual infectious virus or virus mutants that escape the transition into error catastrophe. Here we document...

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Identifiers

PMID: 15016853
DOI: 10.1128/jvi.78.7.3319-3324.2004
PMCID: PMC371084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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