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Article

Upregulation of alveolar epithelial active Na+ transport is dependent on beta2-adrenergic receptor signaling.

Circulation research - 30 Apr 2004

Mutlu Gökhan M, Dumasius Vidas, Burhop James, McShane Pamela J, Meng Fan Jing, Welch Lynn, Dumasius Andrew, Mohebahmadi Nima, Thakuria Gloria, Hardiman Karen, Matalon Sadis, Hollenberg Steven, Factor Phillip

Abstract excerpt

Alveolar epithelial beta-adrenergic receptor (betaAR) activation accelerates active Na+ transport in lung epithelial cells in vitro and speeds alveolar edema resolution in human lung tissue and normal and injured animal lungs. Whether these receptors are essential for alveolar fluid clearance (AFC) or if other mechanisms are sufficient to regulate active transport is unknown. In this study, we report that mice...

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Identifiers

PMID: 15016730
DOI: 10.1161/01.RES.0000125623.56442.20

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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