Article

PAI-1 regulates AT2-mediated re-alveolarization and ion permeability

2023-03-01

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Acute lung injury is characterized by overwhelmingly elevated PAI-1 in both lung edema fluid and the circulating system. The role of increased PAI-1, encoded by Serpine1 gene, in the regeneration of injured lung epithelium has not been understood completely. This study aimed to investigate the role of Serpine1 in the regulation of alveolar type 2 epithelial cell...

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Literature Corpus work: 773f29e1-d9ed-5809-91d6-d2befa8c5d34
DOI: 10.21203/rs.3.rs-2289657/v1

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