Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Directed expression of Cre in alveolar epithelial type 1 cells.

American journal of respiratory cell and molecular biology - 1 Aug 2010

Flodby Per, Borok Zea, Banfalvi Agnes, Zhou Beiyun, Gao Danping, Minoo Parviz, Ann David K, Morrisey Edward E, Crandall Edward D

Abstract excerpt

Pulmonary alveolar epithelium is comprised of two morphologically and functionally distinct cell types, alveolar epithelial type (AT) I and AT2 cells. Genetically modified mice with cell-specific Cre/loxP-mediated knockouts of relevant genes in each respective cell type would be useful to help elucidate the relative contributions of AT1 versus AT2 cells to alveolar homeostasis. Cre has previously been efficiently...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epithelial Cells
Share to Gene Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Integrases

Share to Mice, Transgenic

Share to Models, Biological

Share to Pulmonary Alveoli

Share to Tissue Distribution

Source

Open in PubMed Open full text

Identifiers

PMID: 19767448
DOI: 10.1165/rcmb.2009-0226OC
PMCID: PMC2937230

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Directed expression of Cre in alveolar epithelial type 1 cells.PMID 19767448Read ↗

Airway-specific inducible transgene expression using aerosolized doxycycline.Semantic proximity Read ↗

Wnt5a Promotes AT1 and Represses AT2 Lineage-Specific Gene Expression in a Cell-Context-Dependent MannerSemantic proximity Read ↗

Modulation of Lung Epithelial Cell Function Using Conditional and Inducible Transgenic Approaches.Semantic proximity Read ↗

Type II pneumocyte-restricted green fluorescent protein expression after lentiviral transduction of lung epithelial cells.Semantic proximity Read ↗

Efficient Adeno-associated Virus–mediated Transgenesis in Alveolar Stem Cells and Associated NichesSemantic proximity Read ↗

Surfactant protein-C chromatin-bound green fluorescence protein reporter mice reveal heterogeneity of surfactant protein C-expressing lung cells.Semantic proximity Read ↗

Generation of Plvap-CreER and Car4-CreER for genetic targeting of distinct lung capillary populations.Semantic proximity Read ↗

An inducible hACE2 transgenic mouse model recapitulates SARS-CoV-2 infection and pathogenesis in vivoSemantic proximity Read ↗

GRAMD2 <sup>+</sup> alveolar type I cell plasticity facilitates cell state transitions in organoid cultureSemantic proximity Read ↗

Modulation of Myeloid Cell Function Using Conditional and Inducible Transgenic Approaches.Semantic proximity Read ↗

Transient in utero disruption of cystic fibrosis transmembrane conductance regulator causes phenotypic changes in alveolar type II cells in adult rats.Semantic proximity Read ↗

Conditional Expression of Genes in the Respiratory Epithelium in Transgenic MiceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.