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Article

A novel missense germline mutation in exon 2 of the hMSH2 gene in a HNPCC family from Southern Italy.

Cancer letters - 8 Jun 2005

Baudi Francesco, Fersini Giuseppina, Lavecchia Annamaria, Terracciano Rosa, Leone Francarlo, Quaresima Barbara, Faniello Maria C, De Paola Loredana, Doldo Patrizia, Cuda Giovanni, Costanzo Francesco, Venuta Salvatore

Abstract excerpt

Germline mutations within the mismatch repair (MMR) genes are generally found in colorectal cancer (CRC) patients with a positive family history for the presence of the neoplasia. Clinical standard criteria have been established to define hereditary-non-polyposis-colorectal cancer (HNPCC)-prone families. Interestingly, the number of MMR gene mutations found in kindreds not fulfilling these criteria is still...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15896463
DOI: 10.1016/j.canlet.2004.09.051

Genes

MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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