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Article

Mutations in DNA mismatch repair genes are not responsible for microsatellite instability in most sporadic endometrial carcinomas.

Cancer research - 1 Dec 1995

Katabuchi H, van Rees B, Lambers A R, Ronnett B M, Blazes M S, Leach F S, Cho K R, Hedrick L

Abstract excerpt

Endometrial carcinoma is the second most common tumor type in women with hereditary nonpolyposis colorectal carcinoma. Microsatellite instability (MI) has been observed in the inherited (hereditary nonpolyposis colorectal carcinoma-associated) form of endometrial carcinoma as well as in approximately 20% of presumably sporadic cases. Recent studies suggest that MI in many cell lines or xenografts derived from...

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PMID: 7585634

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Mutations in DNA mismatch repair genes are not responsible for microsatellite instability in most sporadic endometrial carcinomas.PMID 7585634Read ↗

Absence of mutations in DNA mismatch repair genes in sporadic endometrial tumors with microsatellite instability.Semantic proximity Read ↗

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Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas.Semantic proximity Read ↗

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Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability.Semantic proximity Read ↗

Hereditary and somatic DNA mismatch repair gene mutations in sporadic endometrial carcinomaSemantic proximity Read ↗

Pathologic features of endometrial carcinoma associated with HNPCC: a comparison with sporadic endometrial carcinoma.Semantic proximity Read ↗

MLH1 Promoter Methylation and Gene Silencing is the Primary Cause of Microsatellite Instability in Sporadic Endometrial CancersSemantic proximity Read ↗

Molecular epidemiological and mutational analysis of DNA mismatch repair (MMR) genes in endometrial cancer patients with HNPCC-associated familial predisposition to cancer.Semantic proximity Read ↗

Clinical and pathological significance of microsatellite instability in sporadic endometrial carcinoma.Semantic proximity Read ↗

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