Article
Mutations in DNA mismatch repair genes are not responsible for microsatellite instability in most sporadic endometrial carcinomas.
Cancer research - 1 Dec 1995
Katabuchi H, van Rees B, Lambers A R, Ronnett B M, Blazes M S, Leach F S, Cho K R, Hedrick L
Abstract excerpt
Endometrial carcinoma is the second most common tumor type in women with hereditary nonpolyposis colorectal carcinoma. Microsatellite instability (MI) has been observed in the inherited (hereditary nonpolyposis colorectal carcinoma-associated) form of endometrial carcinoma as well as in approxima...
Topics
- Adult
- Aged
- Aged, 80 and over
- Base Sequence
- DNA Mutational Analysis
- DNA Probes
- DNA Repair
- DNA, Neoplasm
- DNA, Satellite
- DNA-Binding Proteins
- Endometrial Neoplasms
- Female
- Humans
- Middle Aged
- Molecular Sequence Data
- MutS Homolog 2 Protein
- Mutation
- Open Reading Frames