Article
p53 expression is decreased in primary breast carcinomas with microsatellite instability.
Breast cancer research and treatment - 1 Jun 2002
Pizzi Claudia, Panico Luigi, De Marchis Laura, Mastranzo Paolo, Di Maio Massimo, D'Amico Cristina, Limite Gennaro, Pettinato Guido, Cocozza Sergio, Bianco Angelo Raffaele, Contegiacomo Alma
Abstract excerpt
p53 and p185 expression in primary breast cancer with microsatellite instability (MSI) is still largely unexplored. To investigate the relationship between these oncoproteins and the pathways of genomic instability, we examined 52 primary invasive breast cancers stratified by the presence and absence of MSI. We determined the status of eight microsatellite loci using radioactive and silver staining methods, and...
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