Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas.

Human molecular genetics - 1 Nov 1995

Børresen A L, Lothe R A, Meling G I, Lystad S, Morrison P, Lipford J, Kane M F, Rognum T O, Kolodner R D

Abstract excerpt

Microsatellite instability is frequently seen in tumors from patients with hereditary nonpolyposis colorectal cancer (HNPCC). Germline mutations in the mismatch repair gene hMSH2 account for approximately 50% of these cases. Tumors from sporadic cases also exhibit this microsatellite instability...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Fungal Proteins

Share to Molecular Sequence Data

Share to Mutation

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 8589682
DOI: 10.1093/hmg/4.11.2065

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-8589682-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas.PMID 8589682Read ↗

Microsatellite instability in human solid tumors.Semantic proximity Read ↗

Mutations in MLH1 are more frequent than in MSH2 in sporadic colorectal cancers with microsatellite instability.Semantic proximity Read ↗

Infrequent hMSH2 mutations in sporadic gastric adenocarcinoma with microsatellite instability.Semantic proximity Read ↗

Microsatellite instability and mutation analysis of hMSH2 and hMLH1 in patients with sporadic, familial and hereditary colorectal cancerSemantic proximity Read ↗

Microsatellite instability in human solid tumors.Semantic proximity Read ↗

Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability.Semantic proximity Read ↗

Microsatellite instability and mutations in DNA mismatch repair genes in sporadic colorectal cancers.Semantic proximity Read ↗

[Microsatellite instability--a new aspects in genetics and molecular biology of hereditary nonpolyposis and sporadic colorectal tumors].Semantic proximity Read ↗

Novel hMSH2, hMSH6 and hMLH1 gene mutations and microsatellite instability in sporadic colorectal cancer.Semantic proximity Read ↗

Microsatellite Instability and hMLH1 and hMSH2 Expression Analysis in Familial and Sporadic Colorectal CancerSemantic proximity Read ↗

Sequence analysis of the mismatch repair gene hMSH6 in the germline of patients with familial and sporadic colorectal cancer.Semantic proximity Read ↗

A meta-analysis of the prevalence of somatic mutations in the hMLH1 and hMSH2 genes in colorectal cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.