Article
Role of Src-induced dynamin-2 phosphorylation in caveolae-mediated endocytosis in endothelial cells.
The Journal of biological chemistry - 7 May 2004
Shajahan Ayesha N, Timblin Barbara K, Sandoval Raudel, Tiruppathi Chinnaswamy, Malik Asrar B, Minshall Richard D
Abstract excerpt
Albumin transcytosis, a determinant of transendothelial permeability, is mediated by the release of caveolae from the plasma membrane. We addressed the role of Src phosphorylation of the GTPase dynamin-2 in the mechanism of caveolae release and albumin transport. Studies were made in microvascular endothelial cells in which the uptake of cholera toxin subunit B, a marker of caveolae, and (125)I-albumin was used...
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