Article
Src kinase regulates the integrity and function of the Golgi apparatus via activation of dynamin 2.
Proceedings of the National Academy of Sciences of the United States of America - 30 Mar 2010
Weller Shaun G, Capitani Mirco, Cao Hong, Micaroni Massimo, Luini Alberto, Sallese Michele, McNiven Mark A
Abstract excerpt
The size and integrity of the Golgi apparatus is maintained via a tightly controlled regulation of membrane traffic using a variety of different signaling and cytoskeletal proteins. We have recently observed that activation of c-Src has profound effects on Golgi structure, leading to dramatically vesiculated cisternae in a variety of cell types. As the large GTPase dynamin (Dyn2) has been implicated in Golgi...
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