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Article

Trafficking of Lyn through the Golgi caveolin involves the charged residues on alphaE and alphaI helices in the kinase domain.

The Journal of cell biology - 7 Jun 2004

Kasahara Kousuke, Nakayama Yuji, Ikeda Kikuko, Fukushima Yuka, Matsuda Daisuke, Horimoto Shinya, Yamaguchi Naoto

Abstract excerpt

Src-family kinases, known to participate in signaling pathways of a variety of surface receptors, are localized to the cytoplasmic side of the plasma membrane through lipid modification. We show here that Lyn, a member of the Src-family kinases, is biosynthetically transported to the plasma membrane via the Golgi pool of caveolin along the secretory pathway. The trafficking of Lyn from the Golgi apparatus to the...

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Identifiers

PMID: 15173188
DOI: 10.1083/jcb.200403011
PMCID: PMC2172378

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Trafficking of Lyn through the Golgi caveolin involves the charged residues on alphaE and alphaI helices in the kinase domain.PMID 15173188Read ↗

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