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Article

Requirement of the SH4 and tyrosine-kinase domains but not the kinase activity of Lyn for its biosynthetic targeting to caveolin-positive Golgi membranes.

Biochimica et biophysica acta - 1 Oct 2009

Ikeda Kikuko, Nakayama Yuji, Ishii Mayuko, Obata Yuuki, Kasahara Kousuke, Fukumoto Yasunori, Yamaguchi Naoto

Abstract excerpt

BACKGROUND: The Src-family non-receptor-type tyrosine kinase Lyn, which is often associated with chemotherapeutic resistance in cancer, localizes not only to the plasma membrane but also Golgi membranes. Recently, we showed that Lyn, which is synthesized in the cytosol, is transported from the Go...

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Source

Identifiers

PMID: 19619611
DOI: 10.1016/j.bbagen.2009.07.009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19619611-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Requirement of the SH4 and tyrosine-kinase domains but not the kinase activity of Lyn for its biosynthetic targeting to caveolin-positive Golgi membranes.PMID 19619611Read ↗

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