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Article

Regulatory role of dynamin-2 in VEGFR-2/KDR-mediated endothelial signaling.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Oct 2005

Bhattacharya Resham, Kang-Decker Ningling, Hughes Deborah A, Mukherjee Priyabrata, Shah Vijay, McNiven Mark A, Mukhopadhyay Debabrata

Abstract excerpt

Vascular endothelial growth factor receptor-2 (VEGFR-2, also known as KDR) is a receptor tyrosine kinase (RTK) regulating mitogenic, chemotactic, permeability, and survival signals in vascular endothelial cells (EC) in response to its ligand, vascular permeability factor/VEGF (VPF/VEGF), arguably the most important angiogenic cytokine. However, the compartmentalization of KDR in EC and the mechanisms regulating...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16049137
DOI: 10.1096/fj.05-3889fje

Genes

KDR
EEA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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