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Article

Peroxisome proliferator and retinoid signaling pathways co-regulate preadipocyte phenotype and survival.

Proceedings of the National Academy of Sciences of the United States of America - 1 Mar 1994

Chawla A, Lazar M A

Abstract excerpt

Culture of mouse 3T3-L1 preadipocytes in medium containing delipidated bovine calf serum caused the cells to elongate and divide after reaching confluency. The continued proliferation correlated with sustained expression of the c-myc gene, which was repressed in control cells. Exposure of the cells to activators of peroxisome proliferator-activated receptor (PPAR), including clofibrate, WY-14,643, and...

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Identifiers

PMID: 8127882
DOI: 10.1073/pnas.91.5.1786
PMCID: PMC43248

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