Article
Frontotemporal dementia and mitochondrial DNA transitions.
Neurobiology of disease - 1 Mar 2004
Grazina Manuela, Silva Filipe, Santana Isabel, Santiago Beatriz, Mendes Cândida, Simões Marta, Oliveira Miguel, Cunha Luís, Oliveira Catarina
Abstract excerpt
Frontotemporal dementia (FTD) is the second most common type of primary degenerative dementia. Some patients present an overlap between Alzheimer's disease (AD) and FTD both in neuropathological and clinical aspects. This may suggest a similar overlap in physiopathology, namely an involvement of mitochondrial DNA (mtDNA) in FTD, as it has been associated to AD. To determine if mtDNA is involved in FTD, we...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
