Mitochondrial DNA sequence analysis of four Alzheimer's and Parkinson's disease patients.

doi:10.1002/(SICI)1096-8628(19960122)61:3<283::AID-AJMG15>3.0.CO;2-P

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Article

Mitochondrial DNA sequence analysis of four Alzheimer's and Parkinson's disease patients.

American journal of medical genetics - 22 Jan 1996

Brown M D, Shoffner J M, Kim Y L, Jun A S, Graham B H, Cabell M F, Gurley D S, Wallace D C

Abstract excerpt

The mitochondrial DNA (mtDNA) sequence was determined on 3 patients with Alzheimer's disease (AD) exhibiting AD plus Parkinson's disease (PD) neuropathologic changes and one patient with PD. Patient mtDNA sequences were compared to the standard Cambridge sequence to identify base changes. In the...

Topics

Alzheimer Disease
Amino Acid Sequence
DNA, Mitochondrial
Humans
Molecular Sequence Data
Mutation
Parkinson Disease
Sequence Analysis, DNA

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