Article
Characterization of the nuclear export signal of polypyrimidine tract-binding protein.
The Journal of biological chemistry - 22 Mar 2002
Li Bin, Yen T S Benedict
Abstract excerpt
The polypyrimidine tract-binding protein (PTB) is a nuclear protein that regulates alternative splicing. In addition, it plays a role in the cytoplasm during infection by some viruses and functions as a positive effector of hepatitis B virus RNA export. Thus, it presumably contains a nuclear export signal (NES). Using a heterokaryon export assay in transfected cultured cells, we have shown that the N-terminal 25...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
