Article
Genome-wide differences between microsatellite stable and unstable colorectal tumors.
Carcinogenesis - 1 Mar 2006
Camps Jordi, Armengol Gemma, del Rey Javier, Lozano Juan José, Vauhkonen Hanna, Prat Esther, Egozcue Josep, Sumoy Lauro, Knuutila Sakari, Miró Rosa
Abstract excerpt
Genomic copy number changes are frequently found in cancers and they have been demonstrated to contribute to carcinogenesis; and it is widely accepted that tumors with microsatellite instability (MSI) are genetically stable and mostly diploid. In the present study we compared the copy number alterations and the gene-expression profiles of microsatellite stable (MSS) and MSI colorectal tumors. A total number of 31...
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