Article
Lack of peroxisomal catalase causes a progeric phenotype in Caenorhabditis elegans.
The Journal of biological chemistry - 7 May 2004
Petriv Oleh I, Rachubinski Richard A
Abstract excerpt
Studies using the nematode Caenorhabditis elegans as a model system to investigate the aging process have implicated the insulin/insulin-like growth factor-I signaling pathway in the regulation of organismal longevity through its action on a subset of target genes. These targets can be classified into genes that shorten or extend life-span upon their induction. Genes that shorten life-span include a variety of...
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