Article
[Value of fecal and blood adenomatous polyposis coli gene and K-ras gene mutation detection in colorectal neoplasm screening].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 1 Jul 2007
Zhan Jun, Li Xin, Yu Zhong, Yuan Yu-hong, Hou Jing
Abstract excerpt
OBJECTIVE: To explore the value of detection of adenomatous polyposis coli (APC) gene and K-ras gene mutations in fecal and blood samples in colorectal neoplasm screening. METHODS: From 84 subjects undergoing colonoscopic examination (including 31 with colorectal carcinoma, 26 with colorectal adenoma, and 27 healthy subjects) between October, 2003 and March, 2004, 5 ml of heparinized peripheral blood and 3-5 g...
Topics
- Adenomatous Polyposis Coli
- Case-Control Studies
- Colorectal Neoplasms
- DNA
- Feces
- Female
- Genes, ras
- Humans
- Male
- Middle Aged
- Mutation
