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Article

Non-redundancy of cytidine deaminases in class switch recombination.

European journal of immunology - 1 Mar 2004

Fugmann Sebastian D, Rush James S, Schatz David G

Abstract excerpt

Class switch recombination (CSR), somatic hypermutation, and gene conversion are immunoglobulin diversification mechanisms that are strictly dependent on the activity of the activation-induced cytidine deaminase (AID). The precise role and substrate(s) of AID in these processes remain to be well defined. The closest homologue of AID is APOBEC-1, a bona fide mRNA-editing enzyme, which shares with AID the ability...

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Identifiers

PMID: 14991614
DOI: 10.1002/eji.200324418

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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