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Article

High frequency of polymorphism Arg753Gln of the Toll-like receptor-2 gene detected by a novel allele-specific PCR.

Journal of molecular medicine (Berlin, Germany) - 1 Jun 2003

Schröder Nicolas W J, Hermann Corinna, Hamann Lutz, Göbel Ulf B, Hartung Thomas, Schumann Ralf R

Abstract excerpt

The recently described family of Toll-like receptors (TLRs) plays a major role in innate immunity by mediating inflammatory reactions against a wide array of pathogens. TLR-2 is reported to interact with various bacterial partial structures including lipoproteins, peptidoglycan, and lipoteichoic acid. Two polymorphisms of the TLR-2 gene have recently been described: Arg753Gln, correlated with the incidence of...

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PMID: 12743710
DOI: 10.1007/s00109-003-0443-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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