Article
Characterization and investigation of single nucleotide polymorphisms and a novel TLR2 mutation in the human TLR2 gene.
Human molecular genetics - 15 May 2007
Merx Sabine, Neumaier Michael, Wagner Hermann, Kirschning Carsten J, Ahmad-Nejad Parviz
Abstract excerpt
In the innate immune system, TLR2 plays a central role for the response to a wide variety of microbial and endogenous danger signals. A considerable number of genetic polymorphisms within the human TLR2 gene have been reported in non-coding and coding sequences. Except for the Arg753Gln variant,...
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