Article
Microsatellite polymorphisms in intron 2 of the toll-like receptor 2 gene and their association with susceptibility to pulmonary tuberculosis in Han Chinese.
Clinical chemistry and laboratory medicine - 1 Jun 2010
Xue Yun, Jin Lei, Li A-Zhong, Wang Hua-Jun, Li Meng, Zhang Yu-Xiang, Wang Yu, Li Ji-Cheng
Abstract excerpt
BACKGROUND: Toll-like receptor 2 (TLR2) is essential for the immune response to tuberculosis (TB). The goal of the present study was to investigate whether the guanine-thymine (GT) repeat microsatellite polymorphism in intron 2 of the TLR2 gene might be correlated with susceptibility to TB in Han Chinese. METHODS: The number of (GT)n repeats was determined by gene scanning from 244 patients with TB and 233...
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