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Article

Influence of Intron II microsatellite polymorphism in human toll-like receptor 2 gene in leprosy.

Human immunology - 1 Aug 2013

Suryadevara Naveen Chandra, Neela Venkata Sanjeev Kumar, Devalraju Kamakshi Prudhula, Jain Suman, SivaSai Krovvidi S R, Valluri Vijaya Lakshmi, Jonnalagada Subbanna, Anandaraj M P J S

Abstract excerpt

Leprosy is a chronic granulomatous infection caused by the obligate intracellular organism Mycobacterium leprae. TLR2 plays a key role when activated by M. leprae lipoproteins initiating protective responses which induce bacterial killing and therefore control of disease spread. Microsatellite polymorphisms in intron2 of TLR2 gene have been reported to be associated with development of clinical features of...

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PMID: 23619473
DOI: 10.1016/j.humimm.2013.04.009

Genes

TLR2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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