Article
Obesity in BSB mice is correlated with expression of genes for iron homeostasis and leptin.
Obesity research - 1 Feb 2004
Farahani Poupak, Chiu Sally, Bowlus Christopher L, Boffelli Dario, Lee Eric, Fisler Janis S, Krauss Ronald M, Warden Craig H
Abstract excerpt
OBJECTIVE: We searched for genes whose alleles cause obesity and novel pathways correlated with obesity. RESEARCH METHODS AND PROCEDURES: BSB mice are a model of complex obesity due to interactions among genes from C57BL/6J (B) and Mus spretus (SPRET) in (B x SPRET) x B backcross mice. Stringent criteria identified 50 genes differentially expressed in epididymal adipose tissue from 7 pairs of lean vs. obese BSB...
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