Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reciprocal hemizygosity analysis of mouse hepatic lipase reveals influence on obesity.

Obesity research - 1 Feb 2004

Farahani Poupak, Fisler Janis S, Wong Howard, Diament Adam L, Yi Nengjun, Warden Craig H

Abstract excerpt

OBJECTIVES: We previously demonstrated coincident quantitative trait loci (QTLs) for percentage body fat, plasma hepatic lipase (HL) activity, and plasma cholesterol on mouse chromosome 7. In the present study, we investigated whether hepatic lipase (Lipc) is an obesity gene, whether Lipc interacts with an unknown gene on chromosome 7, and how HL activity is linked to the chromosome 7 locus. RESEARCH METHODS AND...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholesterol
Share to Crosses, Genetic
Share to Genetic Linkage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipase

Share to Mice, Inbred Strains

Share to Obesity

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Identifiers

PMID: 14981222
DOI: 10.1038/oby.2004.37

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reciprocal hemizygosity analysis of mouse hepatic lipase reveals influence on obesity.PMID 14981222Read ↗

Epistatic interaction between two nonstructural loci on chromosomes 7 and 3 influences hepatic lipase activity in BSB mice.Semantic proximity Read ↗

Identification of four chromosomal loci determining obesity in a multifactorial mouse model.Semantic proximity Read ↗

Mouse hepatic lipase alleles with variable effects on lipoprotein composition and size.Semantic proximity Read ↗

Multiple linked mouse chromosome 7 loci influence body fat mass.Semantic proximity Read ↗

Coincidence of genetic loci for plasma cholesterol levels and obesity in a multifactorial mouse model.Semantic proximity Read ↗

Genetic architecture of adiposity in the cross of LG/J and SM/J inbred mice.Semantic proximity Read ↗

Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model.Semantic proximity Read ↗

Characterization of epistasis influencing complex spontaneous obesity in the BSB model.Semantic proximity Read ↗

Mouse models of inherited lipodystrophy.Semantic proximity Read ↗

Obesity in BSB mice is correlated with expression of genes for iron homeostasis and leptin.Semantic proximity Read ↗

Quantitative trait locus mapping of genetic modifiers of metabolic syndrome and atherosclerosis in low-density lipoprotein receptor-deficient mice: identification of a locus for metabolic syndrome and increased atherosclerosis on chromosome 4.Semantic proximity Read ↗

A novel mouse Chromosome 2 congenic strain with obesity phenotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.