Article
Identification of positional candidate genes for body weight and adiposity in subcongenic mice.
Physiological genomics - 19 Sept 2007
Chiu Sally, Kim Kyoungmi, Haus Kari A, Espinal Glenda M, Millon Lee V, Warden Craig H
Abstract excerpt
We previously constructed a congenic mouse, B6.S-D2Mit194-D2Mit311 (B6.S-2) with 27 Mb of SPRET/Ei donor DNA on distal chromosome 2 in a C57BL/6J background that captured an obesity quantitative trait locus (QTL). Mice homozygous for SPRET/Ei alleles at the donor region had decreased body weight and obesity-related phenotypes (Diament AL, Farahani P, Chiu S, Fisler J, Warden CH. Mamm Genome 15: 452-459, 2004). In...
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