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Article

Mutation and allelic loss of the p53 gene in endometrial carcinoma. Incidence and outcome in 92 surgical patients.

Cancer - 1 Jul 1995

Kihana T, Hamada K, Inoue Y, Yano N, Iketani H, Murao S, Ukita M, Matsuura S

Abstract excerpt

BACKGROUND: Alterations of the p53 gene are involved in the development of diverse human malignancies, but their incidence and clinicopathologic features are still not well characterized for endometrial carcinoma. METHODS: To investigate the clinicopathologic significance of p53, mutations and loss of heterozygosity (LOH) in endometrial carcinoma in 92 patients with this disease were examined. RESULTS: Mutations...

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Identifiers

PMID: 8630879
DOI: 10.1002/1097-0142(19950701)76:1<72::aid-cncr2820760110>3.0.co;2-3

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Source receipt: pubmed, retrieved 7 Sept 2026.

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