Article
Mutation and allelic loss of the p53 gene in endometrial carcinoma. Incidence and outcome in 92 surgical patients.
Cancer - 1 Jul 1995
Kihana T, Hamada K, Inoue Y, Yano N, Iketani H, Murao S, Ukita M, Matsuura S
Abstract excerpt
BACKGROUND: Alterations of the p53 gene are involved in the development of diverse human malignancies, but their incidence and clinicopathologic features are still not well characterized for endometrial carcinoma. METHODS: To investigate the clinicopathologic significance of p53, mutations and lo...
Topics
- Alleles
- Base Sequence
- Carcinoma
- DNA, Neoplasm
- Endometrial Hyperplasia
- Endometrial Neoplasms
- Female
- Genes, p53
- Humans
- Incidence
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Prognosis
- Proportional Hazards Models
- Survival Analysis