Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

New polymorphisms of human CD80 and CD86: lack of association with rheumatoid arthritis and systemic lupus erythematosus.

Genes and immunity - 1 Oct 2000

Matsushita M, Tsuchiya N, Oka T, Yamane A, Tokunaga K

Abstract excerpt

The crucial role of costimulatory molecules, CD28, CTLA-4, CD80 and CD86, for T cell activation and inhibition has been established. In the previous study, we reported the results of a polymorphism screening of human CTLA-4 gene. In this study, we screened for polymorphisms of human CD28, CD80 and CD86 genes, and detected that polymorphisms were tested for the association with rheumatoid arthritis (RA) and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Arthritis, Rheumatoid
Share to B7-1 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to B7-2 Antigen

Share to CD28 Antigens

Share to Lupus Erythematosus, Systemic

Share to Membrane Glycoproteins

Share to Polymorphism, Single-Stranded Conformational

Source

Identifiers

PMID: 11196673
DOI: 10.1038/sj.gene.6363704

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

New polymorphisms of human CD80 and CD86: lack of association with rheumatoid arthritis and systemic lupus erythematosus.PMID 11196673Read ↗

CD80 and CD86 polymorphisms in populations of various ancestries: 5 new CD80 promoter alleles.Semantic proximity Read ↗

Association of CTLA-4 but not CD28 gene polymorphisms with systemic lupus erythematosus in the Japanese population.Semantic proximity Read ↗

Association of common T cell activation gene polymorphisms with multiple sclerosis in Australian patients.Semantic proximity Read ↗

CD28 Genetic Variants Increase Susceptibility to Diabetic Kidney Disease in Chinese Patients with Type 2 Diabetes: A Cross-Sectional Case Control Study.Semantic proximity Read ↗

CTLA-4 and CD86 genetic variants and haplotypes in patients with rheumatoid arthritis in southeastern China.Semantic proximity Read ↗

Polymorphisms in CD28, CTLA-4, CD80 and CD86 genes may influence the risk of multiple sclerosis and its age of onset.Semantic proximity Read ↗

Technical note: linkage disequilibrium and disease-associated CTLA4 gene polymorphisms.Semantic proximity Read ↗

Predicting the functional consequences of genetic variants in co-stimulatory ligand B7-1 using in-silico approaches.Semantic proximity Read ↗

CD86 +1057G/A polymorphism and risk of chronic immune thrombocytopenia.Semantic proximity Read ↗

Five functional polymorphisms of B7/CD28 co-signaling molecules alter susceptibility to colorectal cancer.Semantic proximity Read ↗

Absence of association between CD86 +1057G/A polymorphism and coronary artery disease.Semantic proximity Read ↗

Lack of association between CD28/CTLA-4 gene polymorphisms and atopic asthma in the Japanese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.